ACAP2

Across TCGA patient cohorts, ACAP2 mutation is significantly associated with the RNA expression of many other genes, with 3,362 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACAP2-associated genes across cancer lineages are DYNLT3P2, RNA5SP531, and SNRPGP8. Each is linked with ACAP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ACAP2-to-partner and partner-to-ACAP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DYNLT3P2 grouped by ACAP2-low versus ACAP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACAP2→partner) and Y-score (partner→ACAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DYNLT3P2 →	+0.238	+1.704	.001	.007	3	3
LIHC	RNA5SP531 →	+0.312	+5.584	<.001	.001	3	2
LIHC	SNRPGP8 →	+0.112	+4.894	<.001	.004	3	2
LIHC	EEF1A1P37 →	+0.056	+4.293	<.001	.009	3	2
UCEC	LINC01050 →	+0.140	+1.586	.003	.005	3	2
LUAD	SPTLC1P3 →	+0.325	+4.319	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,362 associations by consensus.

DYNLT3P2 by ACAP2 expression — UCEC

Explore this box plot interactively →