ACAP1

Across TCGA patient cohorts, ACAP1 protein abundance is significantly associated with the protein abundance of many other proteins, with 24,069 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ACAP1-associated proteins across cancer lineages are RGS19, SKAP2, and SPN. Each is linked with ACAP1 in more than 9 cancer types. Because this analysis shows association rather than direction, both ACAP1-to-partner and partner-to-ACAP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACAP1 versus RGS19 in GBM, with a Pearson correlation of 0.54.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ACAP1→partner) and Y-score (partner→ACAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RGS19 →	+0.596	+1.039	<.001	<.001	3	10
GBM	SKAP2 →	+1.170	+1.066	<.001	<.001	3	10
OV	SPN →	+0.831	+0.471	<.001	.005	3	10
LSCC	STK10 →	+0.564	+0.706	<.001	<.001	3	10
OV	TNFAIP8L2 →	+0.956	+0.748	<.001	<.001	3	10
GBM	WAS →	+1.056	+1.034	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 24,069 associations by consensus.

ACAP1 vs RGS19 — GBM

Explore this scatter interactively →