ACAP1

Across TCGA cell cohorts, ACAP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,834 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ACAP1-associated GO terms across cancer lineages are Maintenance of protein localization in organelle, ISG15-protein conjugation, and Autophagy of mitochondrion. Each is linked with ACAP1 in more than 10 cancer types. Because this analysis shows association rather than direction, both ACAP1-to-partner and partner-to-ACAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maintenance of protein localization in organelle grouped by ACAP1-low versus ACAP1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACAP1→partner) and Y-score (partner→ACAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Maintenance of protein localization in organelle →	+0.160	+1.642	<.001	<.001	3	11
STOMACH	ISG15-protein conjugation →	+0.203	+1.168	.003	.009	3	9
STOMACH	Autophagy of mitochondrion →	+0.079	+0.885	.001	.003	3	9
SOFT_TISSUE	Maintenance of protein location in cell →	+0.094	+1.074	<.001	<.001	3	9
SOFT_TISSUE	Maintenance of protein location →	+0.093	+0.938	<.001	<.001	3	9
LIVER	Corpus callosum morphogenesis →	+0.075	+1.387	.001	.004	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,834 associations by consensus.

Maintenance of protein localization in organelle by ACAP1 expression — SOFT_TISSUE

Explore this box plot interactively →