ACADVL

Across TCGA pan-cancer cohorts, ACADVL mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated ACADVL data layer compared with 24 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher ACADVL mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated ACADVL expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

CCRCC, HNSC, and UCEC are the cancer types where ACADVL mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	All	1.000	0.729	.017	10	view →
HNSC	OS	Median	All	0.954	1.000	.010	9	view →
UCEC	OS	Quartile	III,IV	0.414	1.000	.038	8	view →
LSCC	DFS	Tertile	II,III,IV	0.811	1.000	.019	6	view →
LUAD	OS	Quartile	All	0.604	0.931	.037	4	view →
GBM	DFS	Tertile	All	0.664	0.848	.042	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

ACADVL–CCRCC (DFS)

Open the CCRCC breakdown →