ACADVL

Across TCGA patient cohorts, ACADVL mutation is significantly associated with the RNA expression of many other genes, with 1,906 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACADVL-associated genes across cancer lineages are SEPTIN14P19, AP1B1P2, and MIR302C. Each is linked with ACADVL in more than 1 cancer types. Because this analysis shows association rather than direction, both ACADVL-to-partner and partner-to-ACADVL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SEPTIN14P19 grouped by ACADVL-low versus ACADVL-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACADVL→partner) and Y-score (partner→ACADVL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SEPTIN14P19 →	+0.054	+5.288	<.001	.006	3	2
BRCA	AP1B1P2 →	+0.454	+6.442	<.001	.001	3	2
HNSC	MIR302C →	+0.697	+5.440	<.001	<.001	3	2
HNSC	SNORD113-9 →	+0.308	+5.351	<.001	.002	3	2
BRCA	MTCO1P49 →	+0.069	+5.020	.001	.009	3	2
UCEC	RNU6-1318P →	+0.222	+2.221	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,906 associations by consensus.

SEPTIN14P19 by ACADVL expression — BRCA

Explore this box plot interactively →