Across TCGA patient cohorts, ACADSB mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACADSB-associated genes across cancer lineages are A-Raf_pS299, Notch1, and EGFR_pY1068. Each is linked with ACADSB in more than 1 cancer types. Because this analysis shows association rather than direction, both ACADSB-to-partner and partner-to-ACADSB results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACADSB→partner) and Y-score (partner→ACADSB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	A-Raf_pS299 →	-0.116	-3.000	.026	.036	3	2
UCEC	Notch1 →	+0.142	+3.179	.021	.010	3	2
UCEC	EGFR_pY1068 →	-0.217	-2.115	.048	.019	3	1
UCEC	eIF4E →	+0.234	+2.115	.010	.019	2	2
UCEC	MSH2 →	-0.224	-2.973	.026	.035	3	1
UCEC	mTOR_pS2448 →	-0.170	-3.439	.009	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Exploration

ACADSB survival (RNA) · tumor vs normal (RNA) · all ACADSB data types