ACADL

Across TCGA cell cohorts, ACADL RNA expression is significantly associated with the go_rna of many other GO terms, with 1,443 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible ACADL-associated GO terms across cancer lineages are Carnitine metabolic process, CoA-linked, Regulation of stem cell population maintenance, and RNA splicing, via transesterification reactions. Each is linked with ACADL in more than 8 cancer types. Because this analysis shows association rather than direction, both ACADL-to-partner and partner-to-ACADL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Carnitine metabolic process, CoA-linked grouped by ACADL-low versus ACADL-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACADL→partner) and Y-score (partner→ACADL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Carnitine metabolic process, CoA-linked →	-0.216	-0.350	.003	.001	3	9
UPPER_AERODIGESTIVE_TRACT	Regulation of stem cell population maintenance →	+0.078	+0.447	<.001	.001	3	8
UPPER_AERODIGESTIVE_TRACT	RNA splicing, via transesterification reactions →	+0.053	+0.242	<.001	.003	3	8
SOFT_TISSUE	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile →	+0.055	+0.990	<.001	<.001	3	8
SOFT_TISSUE	mRNA splicing, via spliceosome →	+0.055	+0.990	<.001	<.001	3	8
SOFT_TISSUE	Negative regulation of mRNA metabolic process →	+0.064	+0.894	<.001	.006	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,443 associations by consensus.

Carnitine metabolic process, CoA-linked by ACADL expression — PANCREAS

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