ACAD8

Across TCGA cell cohorts, ACAD8 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,304 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ACAD8-associated GO terms across cancer lineages are Meiotic chromosome condensation, Valine metabolic process, and L-valine catabolic process. Each is linked with ACAD8 in more than 16 cancer types. Because this analysis shows association rather than direction, both ACAD8-to-partner and partner-to-ACAD8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Meiotic chromosome condensation grouped by ACAD8-low versus ACAD8-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACAD8→partner) and Y-score (partner→ACAD8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Meiotic chromosome condensation →	+0.160	+1.069	<.001	<.001	3	17
LUNG_NSCLC_LUAD	Valine metabolic process →	+0.128	+1.160	<.001	<.001	3	12
LUNG_NSCLC_LUAD	L-valine catabolic process →	+0.128	+1.160	<.001	<.001	3	12
BONE	Pre-mRNA catabolic process →	+0.256	+1.002	<.001	<.001	3	12
OESOPHAGUS	Ether catabolic process →	+0.158	+0.799	.006	.001	2	12
OESOPHAGUS	Glycerol ether catabolic process →	+0.158	+0.799	.006	.001	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,304 associations by consensus.

Meiotic chromosome condensation by ACAD8 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →