ACAD11

Across TCGA patient cohorts, ACAD11 mutation is significantly associated with the RNA expression of many other genes, with 1,695 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACAD11-associated genes across cancer lineages are MIR8053, PRY2, and LINC01943. Each is linked with ACAD11 in more than 2 cancer types. Because this analysis shows association rather than direction, both ACAD11-to-partner and partner-to-ACAD11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR8053 grouped by ACAD11-low versus ACAD11-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACAD11→partner) and Y-score (partner→ACAD11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR8053 →	+0.287	+4.342	<.001	.007	3	3
LGG	PRY2 →	+0.034	+7.977	<.001	.007	3	2
UCEC	LINC01943 →	+0.338	+2.457	.005	.001	3	2
UCEC	LSM10 →	+0.315	+2.346	.001	<.001	3	2
UCEC	NGRN →	+0.457	+2.343	.001	.003	3	2
UCEC	ROR1 →	+0.551	+1.773	.005	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,695 associations by consensus.

MIR8053 by ACAD11 expression — CESC

Explore this box plot interactively →