ACAD11

Across TCGA cell cohorts, ACAD11 mutation is significantly associated with the RNA expression of many other genes, with 60 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ACAD11-associated genes across cancer lineages are BHLHE23, RFPL3, and ELOA3DP. Each is linked with ACAD11 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACAD11-to-partner and partner-to-ACAD11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BHLHE23 grouped by ACAD11-low versus ACAD11-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACAD11→partner) and Y-score (partner→ACAD11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	BHLHE23 →	+1.175	+3.691	<.001	.005	3	2
LARGE_INTESTINE	RFPL3 →	+0.038	+2.925	<.001	.007	3	2
LARGE_INTESTINE	ELOA3DP →	+0.016	+3.103	.008	.004	3	2
URINARY_TRACT	GPR101 →	+0.020	+5.087	<.001	.004	3	1
SOFT_TISSUE	CST9L →	+0.032	+4.369	<.001	.008	3	1
BLOOD_Lymphoma	DEFB129 →	+0.032	+5.247	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 60 associations by consensus.

BHLHE23 by ACAD11 expression — BLOOD_Leukemia

Explore this box plot interactively →