ACAD10

Across TCGA pan-cancer cohorts, ACAD10 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ACAD10 data layer compared with 23 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher ACAD10 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated ACAD10 expression acts as an unfavorable survival marker, although some lineages such as LUAD and PDAC show a favorable association.

LUAD, PDAC, and CCRCC are the cancer types where ACAD10 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	III,IV	1.000	0.308	.001	28	view →
PDAC	OS	Median	III,IV	0.828	0.351	.001	23	view →
CCRCC	OS	Quartile	All	0.964	0.771	.017	16	view →
GBM	DFS	Quartile	All	0.539	0.200	.003	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

ACAD10–LUAD (OS)

Open the LUAD breakdown →