ACAD10

Across TCGA patient cohorts, ACAD10 mutation is significantly associated with the RNA expression of many other genes, with 1,680 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACAD10-associated genes across cancer lineages are MIR6893, GPX4, and CENPM. Each is linked with ACAD10 in more than 2 cancer types. Because this analysis shows association rather than direction, both ACAD10-to-partner and partner-to-ACAD10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6893 grouped by ACAD10-low versus ACAD10-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACAD10→partner) and Y-score (partner→ACAD10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR6893 →	+0.181	+2.230	<.001	.002	3	3
UCEC	GPX4 →	+0.442	+2.316	.001	<.001	3	3
UCEC	CENPM →	+0.507	+1.938	.003	.001	3	3
UCEC	MED31 →	+0.378	+4.108	.001	<.001	3	3
UCEC	TAF9 →	+0.554	+2.828	<.001	.001	3	3
STAD	NDUFB6 →	+0.543	+3.236	.004	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,680 associations by consensus.

MIR6893 by ACAD10 expression — SKCM

Explore this box plot interactively →