ACAD10

Across TCGA patient cohorts, ACAD10 mutation is significantly associated with the total protein of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACAD10-associated genes across cancer lineages are C-Raf, Rab25, and Rictor_pT1135. Each is linked with ACAD10 in more than 2 cancer types. Because this analysis shows association rather than direction, both ACAD10-to-partner and partner-to-ACAD10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C-Raf grouped by ACAD10-low versus ACAD10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACAD10→partner) and Y-score (partner→ACAD10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	C-Raf →	+0.148	+2.584	.005	.010	3	3
UCEC	Rab25 →	-0.389	-1.765	.001	.014	3	2
UCEC	Rictor_pT1135 →	-0.107	-2.222	.005	.010	3	2
UCEC	TFRC →	+0.497	+1.765	.012	.014	3	2
UCEC	Cyclin-B1 →	+0.691	+2.662	.001	<.001	3	2
SKCM	Caspase-8 →	-0.152	-2.415	.008	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

C-Raf by ACAD10 expression — UCEC

Explore this box plot interactively →