ACAD10

Across TCGA cell cohorts, ACAD10 mutation is significantly associated with the RNA expression of many other genes, with 58 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ACAD10-associated genes across cancer lineages are HDGFL1, HHLA1, and OR10AC1. Each is linked with ACAD10 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACAD10-to-partner and partner-to-ACAD10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HDGFL1 grouped by ACAD10-low versus ACAD10-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACAD10→partner) and Y-score (partner→ACAD10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	HDGFL1 →	+0.209	+3.523	.008	.005	3	2
URINARY_TRACT	HHLA1 →	+0.059	+3.506	.001	.006	3	1
URINARY_TRACT	OR10AC1 →	+0.021	+3.700	<.001	.003	3	1
URINARY_TRACT	TPPP2 →	+0.052	+4.372	<.001	<.001	3	1
URINARY_TRACT	CLDN24 →	+0.231	+3.675	<.001	.003	3	1
URINARY_TRACT	LCE3E →	+0.144	+3.050	.003	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 58 associations by consensus.

HDGFL1 by ACAD10 expression — URINARY_TRACT

Explore this box plot interactively →