ACACA

Across TCGA cell cohorts, ACACA RNA expression is significantly associated with the go_rna of many other GO terms, with 4,157 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ACACA-associated GO terms across cancer lineages are Malonyl-CoA biosynthetic process, DNA strand elongation involved in DNA replication, and Nucleosome disassembly. Each is linked with ACACA in more than 18 cancer types. Because this analysis shows association rather than direction, both ACACA-to-partner and partner-to-ACACA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Malonyl-CoA biosynthetic process grouped by ACACA-low versus ACACA-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACACA→partner) and Y-score (partner→ACACA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Malonyl-CoA biosynthetic process →	+0.164	+0.821	<.001	<.001	3	19
SOFT_TISSUE	DNA strand elongation involved in DNA replication →	+0.140	+0.777	.007	.006	3	15
LARGE_INTESTINE	Nucleosome disassembly →	+0.123	+0.848	.001	.001	3	15
KIDNEY	Protein-DNA complex disassembly →	+0.154	+1.014	<.001	.002	3	13
STOMACH	Zymosterol metabolic process →	+0.186	+0.895	.001	.002	3	13
STOMACH	Zymosterol biosynthetic process →	+0.186	+0.895	.001	.002	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,157 associations by consensus.

Malonyl-CoA biosynthetic process by ACACA expression — BREAST

Explore this box plot interactively →