ABTB2

Across TCGA patient cohorts, ABTB2 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,159 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ABTB2-associated proteins across cancer lineages are ABTB2_S67, RASAL3, and RPS27L. Each is linked with ABTB2 in more than 4 cancer types. Because this analysis shows association rather than direction, both ABTB2-to-partner and partner-to-ABTB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABTB2 versus ABTB2_S67 in CCRCC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ABTB2→partner) and Y-score (partner→ABTB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	ABTB2_S67 →	+0.580	+0.964	<.001	<.001	3	5
LSCC	RASAL3 →	-0.386	-0.562	.001	.003	3	3
BRCA	RPS27L →	-0.316	-0.599	<.001	.002	3	3
CCRCC	SEPTIN1_S206 →	-0.630	-0.613	.001	.002	3	3
HNSC	AASS →	-0.460	-0.471	.001	.006	3	3
LSCC	SPCS3 →	-0.489	-0.519	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,159 associations by consensus.

ABTB2 vs ABTB2_S67 — CCRCC

Explore this scatter interactively →