ABTB2

Across TCGA cell cohorts, ABTB2 mutation is significantly associated with the RNA expression of many other genes, with 295 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ABTB2-associated genes across cancer lineages are FCRL4, GIMAP7, and OR10R2. Each is linked with ABTB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABTB2-to-partner and partner-to-ABTB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FCRL4 grouped by ABTB2-low versus ABTB2-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABTB2→partner) and Y-score (partner→ABTB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	FCRL4 →	+0.005	+3.730	<.001	.002	3	1
CNS	GIMAP7 →	+0.029	+3.584	.002	.003	3	1
CNS	OR10R2 →	+0.016	+4.357	<.001	.004	3	1
BLOOD_Leukemia	SULT2A1 →	+0.086	+3.339	.001	.006	3	1
BLOOD_Leukemia	CPN1 →	+0.096	+3.820	.004	.004	3	1
BLOOD_Leukemia	CFHR4 →	+0.095	+3.339	.002	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 295 associations by consensus.

FCRL4 by ABTB2 expression — CNS

Explore this box plot interactively →