ABTB1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ABTB1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,236 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ABTB1-associated genes across cancer lineages are SNX3, COX7A2, and PDE4DIPP4. Each is linked with ABTB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABTB1-to-partner and partner-to-ABTB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABTB1 versus SNX3 in LUAD, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABTB1→partner) and Y-score (partner→ABTB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADSNX3 →+0.417+0.543<.001.00132
LUADCOX7A2 →+0.490+0.391.001.00332
CCRCCPDE4DIPP4 →-0.414-0.710.007.00432
LUADSNORA11B →-0.622-0.418.002.00232
PDACXYLT1 →+0.497+0.767.008.00431
PDACZC3HAV1 →+0.347+0.720.006.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,236 associations by consensus.

ABTB1 vs SNX3 — LUAD

Per-sample scatter of ABTB1 vs SNX3 in LUAD (Pearson r = 0.45).

Explore this scatter interactively →

Exploration