ABT1

Across TCGA cell cohorts, ABT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,986 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ABT1-associated GO terms across cancer lineages are Protein peptidyl-prolyl isomerization, Negative regulation of RNA export from nucleus, and rRNA 5'-end processing. Each is linked with ABT1 in more than 15 cancer types. Because this analysis shows association rather than direction, both ABT1-to-partner and partner-to-ABT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein peptidyl-prolyl isomerization grouped by ABT1-low versus ABT1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ABT1→partner) and Y-score (partner→ABT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Protein peptidyl-prolyl isomerization →	+0.106	+0.585	<.001	<.001	3	16
PANCREAS	Negative regulation of RNA export from nucleus →	+0.132	+0.626	<.001	<.001	3	16
BONE	rRNA 5'-end processing →	+0.145	+0.660	<.001	<.001	3	15
BONE	Endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.145	+0.660	<.001	<.001	3	15
BONE	Endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.134	+0.691	<.001	<.001	3	13
OVARY	Maturation of SSU-rRNA →	+0.108	+0.633	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,986 associations by consensus.

Protein peptidyl-prolyl isomerization by ABT1 expression — PANCREAS

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