ABRAXAS1

Across TCGA patient cohorts, ABRAXAS1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,892 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ABRAXAS1-associated genes across cancer lineages are ZNF346, MRNIP, and ZFP62. Each is linked with ABRAXAS1 in more than 4 cancer types. Because this analysis shows association rather than direction, both ABRAXAS1-to-partner and partner-to-ABRAXAS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABRAXAS1 versus ZNF346 in OV, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABRAXAS1→partner) and Y-score (partner→ABRAXAS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ZNF346 →	+0.689	+0.435	<.001	<.001	3	5
OV	MRNIP →	+0.747	+0.402	.003	.001	3	5
OV	ZFP62 →	+0.702	+0.366	.002	<.001	3	5
OV	UIMC1 →	+0.490	+0.382	<.001	<.001	3	5
LUAD	SUGT1P4-STRA6LP →	+0.513	+0.250	<.001	<.001	3	5
OV	BRD8 →	+0.509	+0.302	.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,892 associations by consensus.

ABRAXAS1 vs ZNF346 — OV

Explore this scatter interactively →