ABRAXAS1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ABRAXAS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,479 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ABRAXAS1-associated GO terms across cancer lineages are Positive regulation of type B pancreatic cell development, DAMP biosynthetic process, and Protein localization to non-motile cilium. Each is linked with ABRAXAS1 in more than 12 cancer types. Because this analysis shows association rather than direction, both ABRAXAS1-to-partner and partner-to-ABRAXAS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of type B pancreatic cell development grouped by ABRAXAS1-low versus ABRAXAS1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ABRAXAS1→partner) and Y-score (partner→ABRAXAS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BREASTPositive regulation of type B pancreatic cell development →-0.274-0.900<.001.002313
LARGE_INTESTINEDAMP biosynthetic process →+0.106+0.884<.001<.001310
CNSProtein localization to non-motile cilium →+0.073+1.095<.001<.001310
UPPER_AERODIGESTIVE_TRACTRegulation of type B pancreatic cell development →-0.136-0.838<.001.001310
LARGE_INTESTINEPurine deoxyribonucleoside monophosphate biosynthetic process →+0.106+0.884<.001<.001310
LUNG_SCLCNegative regulation of beige fat cell differentiation →+0.125+0.895<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,479 associations by consensus.

Positive regulation of type B pancreatic cell development by ABRAXAS1 expression — BREAST

Box plot of Positive regulation of type B pancreatic cell development in ABRAXAS1-low vs ABRAXAS1-high samples in BREAST.

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