ABRACL

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, ABRACL Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated ABRACL data layer compared with 23 for mass-spec protein and 7 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ABRACL Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ABRACL expression acts as an unfavorable survival marker.

HNSC are the cancer types where ABRACL Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCOSMedianAll0.1690.710.00818view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

ABRACL–HNSC (OS)

Kaplan–Meier survival curve for ABRACL mutant vs wild-type samples in HNSC.

Open the HNSC breakdown →

Exploration