ABR

Across TCGA pan-cancer cohorts, ABR mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ABR data layer compared with 26 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher ABR mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated ABR expression acts as an unfavorable survival marker, although some lineages such as UCEC and PDAC show a favorable association.

UCEC, LSCC, and PDAC are the cancer types where ABR mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	0.964	0.846	.006	10	view →
LSCC	OS	Quartile	All	0.732	0.941	.023	9	view →
PDAC	OS	Quartile	II,III,IV	0.971	0.756	.009	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

ABR–UCEC (DFS)

Open the UCEC breakdown →