ABR

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ABR RNA expression is significantly associated with the protein abundance of many other proteins, with 9,978 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ABR-associated proteins across cancer lineages are PITPNA, RABGEF1, and MSR1_S27. Each is linked with ABR in more than 4 cancer types. Because this analysis shows association rather than direction, both ABR-to-partner and partner-to-ABR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABR versus PITPNA in BRCA, with a Pearson correlation of 0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ABR→partner) and Y-score (partner→ABR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAPITPNA →+0.251+0.509.001.00135
BRCARABGEF1 →+0.220+0.518.004.00134
CCRCCMSR1_S27 →+0.746+0.583.001<.00134
PDACSH3BGRL3 →+0.306+0.189.005.00234
OVMYO1C →+0.550+1.074.002<.00134
GBMVPS18 →+0.145+0.352<.001.00334
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,978 associations by consensus.

ABR vs PITPNA — BRCA

Per-sample scatter of ABR vs PITPNA in BRCA (Pearson r = 0.29).

Explore this scatter interactively →

Exploration