ABR

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ABR protein abundance is significantly associated with the RNA expression of many other genes, with 15,261 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ABR-associated genes across cancer lineages are PLCB2, LYL1, and MYO1F. Each is linked with ABR in more than 6 cancer types. Because this analysis shows association rather than direction, both ABR-to-partner and partner-to-ABR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABR versus PLCB2 in OV, with a Pearson correlation of 0.73.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABR→partner) and Y-score (partner→ABR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVPLCB2 →+1.102+0.637.001<.00137
OVLYL1 →+1.107+0.825.001.00436
OVMYO1F →+1.048+0.724.009<.00136
OVSNX20 →+1.064+0.694.004<.00136
OVDPEP2 →+0.854+0.898.002<.00136
OVTMC8 →+1.187+0.637<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,261 associations by consensus.

ABR vs PLCB2 — OV

Per-sample scatter of ABR vs PLCB2 in OV (Pearson r = 0.73).

Explore this scatter interactively →

Exploration