ABO

Across TCGA patient cohorts, ABO protein abundance is significantly associated with the RNA expression of many other genes, with 1,218 significant associations in total. COAD shows the largest number of these associations.

The most reproducible ABO-associated genes across cancer lineages are PGAP4, RNF183, and DEGS2. Each is linked with ABO in more than 1 cancer types. Because this analysis shows association rather than direction, both ABO-to-partner and partner-to-ABO results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABO versus PGAP4 in COAD, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABO→partner) and Y-score (partner→ABO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PGAP4 →	+0.794	+1.027	<.001	<.001	3	2
COAD	RNF183 →	+0.951	+0.879	<.001	<.001	3	2
COAD	DEGS2 →	+0.940	+0.816	<.001	.001	3	2
LUAD	SNRPGP15 →	+0.478	+0.766	.006	<.001	3	2
OV	GNA15 →	+0.780	+1.059	.004	.008	3	2
HNSC	TAF4B →	-0.568	-0.611	.005	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,218 associations by consensus.

ABO vs PGAP4 — COAD

Explore this scatter interactively →