ABLIM3

Across TCGA patient cohorts, ABLIM3 mutation is significantly associated with the total protein of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABLIM3-associated genes across cancer lineages are Rictor_pT1135, ATM, and YAP_pS127. Each is linked with ABLIM3 in more than 2 cancer types. Because this analysis shows association rather than direction, both ABLIM3-to-partner and partner-to-ABLIM3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rictor_pT1135 grouped by ABLIM3-low versus ABLIM3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABLIM3→partner) and Y-score (partner→ABLIM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Rictor_pT1135 →	-0.074	-1.263	.018	.019	3	3
UCEC	ATM →	-0.531	-1.700	<.001	.001	3	3
SKCM	YAP_pS127 →	-0.520	-3.000	.011	.036	3	2
UCEC	Stathmin →	+0.097	+2.169	.021	.003	3	2
UCEC	ASNS →	+0.366	+2.415	<.001	.002	3	2
UCEC	Caspase-7-cleavedD198 →	+0.394	+1.604	.030	.010	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

Rictor_pT1135 by ABLIM3 expression — UCEC

Explore this box plot interactively →