ABLIM2

Across TCGA patient cohorts, ABLIM2 mutation is significantly associated with the total protein of many other genes, with 44 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABLIM2-associated genes across cancer lineages are TFRC, NDRG1_pT346, and p62 Lck ligand. Each is linked with ABLIM2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ABLIM2-to-partner and partner-to-ABLIM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFRC grouped by ABLIM2-low versus ABLIM2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABLIM2→partner) and Y-score (partner→ABLIM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TFRC →	+0.328	+1.700	.038	.040	3	3
UCEC	NDRG1_pT346 →	-0.309	-1.321	.034	.027	3	2
COAD	p62 Lck ligand →	+0.531	+3.178	.005	.010	3	2
COAD	PCNA →	+0.308	+2.820	.011	.035	3	2
UCEC	PDCD4 →	-0.513	-2.584	<.001	<.001	3	2
UCEC	Rab25 →	-0.335	-1.807	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 44 associations by consensus.

TFRC by ABLIM2 expression — UCEC

Explore this box plot interactively →