ABLIM2

Across TCGA cell cohorts, ABLIM2 mutation is significantly associated with the RNA expression of many other genes, with 35 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible ABLIM2-associated genes across cancer lineages are CPXCR1, SPATA31D1, and SERPINA2. Each is linked with ABLIM2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABLIM2-to-partner and partner-to-ABLIM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CPXCR1 grouped by ABLIM2-low versus ABLIM2-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABLIM2→partner) and Y-score (partner→ABLIM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	CPXCR1 →	+0.028	+4.070	.002	.003	3	2
LUNG_SCLC	SPATA31D1 →	+0.506	+4.058	<.001	.007	3	2
BLOOD_Leukemia	SERPINA2 →	+0.021	+4.384	<.001	.006	3	2
BLOOD_Lymphoma	ZNF804B →	+0.013	+4.350	<.001	.005	3	2
LUNG_NSCLC_LUAD	KRT73 →	+0.057	+3.215	<.001	.007	3	2
LUNG_SCLC	SMR3A →	+0.116	+4.058	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

CPXCR1 by ABLIM2 expression — LUNG_SCLC

Explore this box plot interactively →