ABLIM1

Across TCGA patient cohorts, ABLIM1 mutation is significantly associated with the RNA expression of many other genes, with 2,821 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABLIM1-associated genes across cancer lineages are CRYBB2P1, AHSA1, and NUTF2. Each is linked with ABLIM1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ABLIM1-to-partner and partner-to-ABLIM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CRYBB2P1 grouped by ABLIM1-low versus ABLIM1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABLIM1→partner) and Y-score (partner→ABLIM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CRYBB2P1 →	+0.366	+3.063	.003	<.001	3	3
UCEC	AHSA1 →	+0.329	+3.971	.001	<.001	3	3
UCEC	NUTF2 →	+0.341	+1.925	<.001	<.001	3	3
UCEC	GOT1 →	+0.363	+1.957	.001	<.001	3	3
UCEC	C16orf70 →	+0.419	+2.169	<.001	<.001	3	3
SKCM	FBXL15 →	+0.429	+1.879	.002	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,821 associations by consensus.

CRYBB2P1 by ABLIM1 expression — UCEC

Explore this box plot interactively →