ABLIM1

Across TCGA cell cohorts, ABLIM1 mutation is significantly associated with the RNA expression of many other genes, with 83 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ABLIM1-associated genes across cancer lineages are GALR3, TEX44, and SMIM23. Each is linked with ABLIM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABLIM1-to-partner and partner-to-ABLIM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GALR3 grouped by ABLIM1-low versus ABLIM1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABLIM1→partner) and Y-score (partner→ABLIM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GALR3 →	+0.085	+3.212	.002	.006	3	2
KIDNEY	TEX44 →	+0.033	+3.947	<.001	.003	3	1
KIDNEY	SMIM23 →	+0.020	+3.954	<.001	.001	3	1
KIDNEY	IQCM →	+0.032	+3.584	.005	.008	3	1
BREAST	OR10AG1 →	+0.013	+5.169	<.001	.005	3	1
BREAST	OR10J5 →	+0.071	+5.169	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 83 associations by consensus.

GALR3 by ABLIM1 expression — LARGE_INTESTINE

Explore this box plot interactively →