ABL1

Across TCGA patient cohorts, ABL1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,886 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ABL1-associated genes across cancer lineages are PABPC5, LHFPL6, and ECM2. Each is linked with ABL1 in more than 6 cancer types. Because this analysis shows association rather than direction, both ABL1-to-partner and partner-to-ABL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABL1 versus PABPC5 in OV, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABL1→partner) and Y-score (partner→ABL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PABPC5 →	+0.652	+0.414	<.001	<.001	3	7
UCEC	LHFPL6 →	+0.873	+0.196	<.001	<.001	3	7
BRCA	ECM2 →	+1.001	+0.330	<.001	<.001	3	7
CCRCC	CNRIP1 →	+0.796	+0.194	<.001	.002	3	6
CCRCC	MYCT1 →	+0.675	+0.165	<.001	<.001	3	6
CCRCC	ADGRL4 →	+1.077	+0.222	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,886 associations by consensus.

ABL1 vs PABPC5 — OV

Explore this scatter interactively →