ABL1

Across TCGA cell cohorts, ABL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,468 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ABL1-associated GO terms across cancer lineages are Response to oscillatory fluid shear stress, Cellular response to oscillatory fluid shear stress, and Vascular endothelial cell response to oscillatory fluid shear stress. Each is linked with ABL1 in more than 19 cancer types. Because this analysis shows association rather than direction, both ABL1-to-partner and partner-to-ABL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to oscillatory fluid shear stress grouped by ABL1-low versus ABL1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ABL1→partner) and Y-score (partner→ABL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Response to oscillatory fluid shear stress →	+0.189	+0.860	<.001	.002	3	20
LIVER	Cellular response to oscillatory fluid shear stress →	+0.189	+0.860	<.001	.002	3	20
LIVER	Vascular endothelial cell response to oscillatory fluid shear stress →	+0.189	+0.860	<.001	.002	3	20
PANCREAS	Positive regulation of phospholipase C/protein kinase C signal transduction →	+0.383	+0.661	.003	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Negative regulation of cilium assembly →	+0.080	+0.887	.001	.004	3	17
OESOPHAGUS	Nucleic acid transport →	+0.128	+0.928	.002	.009	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,468 associations by consensus.

Response to oscillatory fluid shear stress by ABL1 expression — LIVER

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