ABL1

Across TCGA cell cohorts, ABL1 mutation is significantly associated with the RNA expression of many other genes, with 526 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ABL1-associated genes across cancer lineages are CRYGC, C7orf33, and AVP. Each is linked with ABL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABL1-to-partner and partner-to-ABL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CRYGC grouped by ABL1-low versus ABL1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABL1→partner) and Y-score (partner→ABL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	CRYGC →	+0.587	+4.169	<.001	.008	3	2
STOMACH	C7orf33 →	+0.261	+4.129	.002	.007	3	2
BLOOD_Lymphoma	AVP →	+0.025	+4.209	<.001	.001	3	1
BLOOD_Lymphoma	CEACAM4 →	+0.029	+3.342	<.001	.008	3	1
BLOOD_Lymphoma	CABP5 →	+0.013	+3.867	<.001	.002	3	1
BLOOD_Lymphoma	DEFB129 →	+0.021	+4.247	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 526 associations by consensus.

CRYGC by ABL1 expression — CNS

Explore this box plot interactively →