ABITRAM

Across TCGA cell cohorts, ABITRAM mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ABITRAM-associated genes across cancer lineages are TMCO5A, CCL18, and CD300H. Each is linked with ABITRAM in more than 1 cancer types. Because this analysis shows association rather than direction, both ABITRAM-to-partner and partner-to-ABITRAM results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TMCO5A grouped by ABITRAM-low versus ABITRAM-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABITRAM→partner) and Y-score (partner→ABITRAM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TMCO5A →	+0.026	+5.415	<.001	.004	3	1
LARGE_INTESTINE	CCL18 →	+0.129	+5.415	<.001	.004	3	1
LARGE_INTESTINE	CD300H →	+0.045	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

TMCO5A by ABITRAM expression — LARGE_INTESTINE

Explore this box plot interactively →