ABHD6

Across TCGA patient cohorts, ABHD6 mutation is significantly associated with the RNA expression of many other genes, with 2,233 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABHD6-associated genes across cancer lineages are LINC00604, HSPE1-MOB4, and CWC25. Each is linked with ABHD6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABHD6-to-partner and partner-to-ABHD6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00604 grouped by ABHD6-low versus ABHD6-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD6→partner) and Y-score (partner→ABHD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	LINC00604 →	+0.121	+4.351	.001	.002	3	2
UCEC	HSPE1-MOB4 →	+0.127	+1.740	.004	.007	3	1
UCEC	CWC25 →	+0.374	+3.375	.005	.004	3	1
UCEC	ZNHIT3 →	+0.415	+3.534	.003	.002	3	1
UCEC	CYFIP1 →	+0.642	+2.695	<.001	<.001	3	1
UCEC	TAF9 →	+0.634	+3.087	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,233 associations by consensus.

LINC00604 by ABHD6 expression — SKCM

Explore this box plot interactively →