ABHD6

Across TCGA cell cohorts, ABHD6 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ABHD6-associated genes across cancer lineages are PYDC2, TBC1D21, and OR10W1. Each is linked with ABHD6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABHD6-to-partner and partner-to-ABHD6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PYDC2 grouped by ABHD6-low versus ABHD6-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD6→partner) and Y-score (partner→ABHD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PYDC2 →	+0.145	+5.415	<.001	.004	3	2
LARGE_INTESTINE	TBC1D21 →	+0.020	+6.022	<.001	.001	3	1
LARGE_INTESTINE	OR10W1 →	+0.022	+4.977	<.001	.007	3	1
LARGE_INTESTINE	CCER1 →	+0.012	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

PYDC2 by ABHD6 expression — LARGE_INTESTINE

Explore this box plot interactively →