ABHD5

Across TCGA patient cohorts, ABHD5 RNA expression is significantly associated with the mutation status of many other genes, with 11,564 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABHD5-associated genes across cancer lineages are PTPRT, PIK3CA, and SLIT1. Each is linked with ABHD5 in more than 5 cancer types. Because this analysis shows association rather than direction, both ABHD5-to-partner and partner-to-ABHD5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PTPRT grouped by ABHD5-low versus ABHD5-high in UCEC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD5→partner) and Y-score (partner→ABHD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PTPRT →	+1.358	+0.405	<.001	<.001	3	6
STAD	PIK3CA →	+1.411	+0.324	.004	.003	3	5
UCEC	SLIT1 →	+2.136	+0.642	<.001	<.001	3	5
UCEC	FAT1 →	+1.292	+0.543	<.001	<.001	3	5
BRCA	SCN11A →	+3.481	+0.552	.003	.002	3	4
COAD	HERC2 →	+3.274	+0.349	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,564 associations by consensus.

PTPRT by ABHD5 expression — UCEC

Explore this box plot interactively →