ABHD5

Across TCGA patient cohorts, ABHD5 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABHD5-associated genes across cancer lineages are Endothelial cells, lymphatic Endothelial cells, and mv Endothelial cells. Each is linked with ABHD5 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABHD5-to-partner and partner-to-ABHD5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endothelial cells grouped by ABHD5-low versus ABHD5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD5→partner) and Y-score (partner→ABHD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Endothelial cells →	-0.036	-1.764	.020	.028	3	1
UCEC	lymphatic Endothelial cells →	-0.021	-2.419	.033	.020	3	1
UCEC	mv Endothelial cells →	-0.022	-2.459	.021	.020	3	1
UCEC	pDC →	+0.047	+2.202	.019	.033	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Endothelial cells by ABHD5 expression — UCEC

Explore this box plot interactively →