ABHD5

Across TCGA cell cohorts, ABHD5 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ABHD5-associated genes across cancer lineages are KRTAP17-1, TFDP3, and NEXMIF. Each is linked with ABHD5 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABHD5-to-partner and partner-to-ABHD5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP17-1 grouped by ABHD5-low versus ABHD5-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD5→partner) and Y-score (partner→ABHD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	KRTAP17-1 →	+0.026	+5.369	<.001	.004	3	1
LARGE_INTESTINE	TFDP3 →	+0.024	+4.196	<.001	.002	3	1
LARGE_INTESTINE	NEXMIF →	+0.340	+4.196	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

KRTAP17-1 by ABHD5 expression — SOFT_TISSUE

Explore this box plot interactively →