ABHD2

Across TCGA patient cohorts, ABHD2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,850 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ABHD2-associated genes across cancer lineages are LRRC26, ZNF397, and FCGR1B. Each is linked with ABHD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABHD2-to-partner and partner-to-ABHD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ABHD2 versus LRRC26 in BRCA, with a Pearson correlation of -0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD2→partner) and Y-score (partner→ABHD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LRRC26 →	-1.972	-0.646	.002	.002	3	2
BRCA	ZNF397 →	-0.948	-0.692	<.001	<.001	3	2
BRCA	FCGR1B →	+0.517	+0.447	.004	.005	3	2
BRCA	IFITM9P →	+2.219	+0.604	<.001	.004	3	2
BRCA	COMMD4P1 →	+0.929	+0.579	.001	.005	3	2
BRCA	ATG12P2 →	-0.720	-0.630	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,850 associations by consensus.

ABHD2 vs LRRC26 — BRCA

Explore this scatter interactively →