ABHD2

Across TCGA cell cohorts, ABHD2 mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ABHD2-associated genes across cancer lineages are GTSF1L, IZUMO2, and AMY1B. Each is linked with ABHD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABHD2-to-partner and partner-to-ABHD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GTSF1L grouped by ABHD2-low versus ABHD2-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD2→partner) and Y-score (partner→ABHD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	GTSF1L →	+0.042	+4.467	<.001	.004	3	1
SKIN	IZUMO2 →	+0.129	+4.684	<.001	.002	3	1
SKIN	AMY1B →	+0.034	+4.930	<.001	.001	3	1
SKIN	FAM9A →	+0.139	+4.684	<.001	.002	3	1
SKIN	AMY1A →	+0.019	+4.415	<.001	.007	3	1
LARGE_INTESTINE	SLC15A5 →	+0.017	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

GTSF1L by ABHD2 expression — SKIN

Explore this box plot interactively →