ABHD2

Across TCGA cell cohorts, ABHD2 mutation is significantly associated with the mutation status of many other genes, with 3,031 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ABHD2-associated genes across cancer lineages are HINFP, LTA4H, and PI4KB. Each is linked with ABHD2 in more than 4 cancer types. Because this analysis shows association rather than direction, both ABHD2-to-partner and partner-to-ABHD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HINFP grouped by ABHD2-low versus ABHD2-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD2→partner) and Y-score (partner→ABHD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	HINFP →	+5.053	+4.239	.007	.007	1	5
BLOOD_Lymphoma	LTA4H →	+5.584	+5.014	.003	.003	1	5
BLOOD_Lymphoma	PI4KB →	+5.584	+5.014	.003	.003	1	4
BLOOD_Lymphoma	ZNF653 →	+5.584	+5.014	.003	.003	1	4
BLOOD_Lymphoma	DDX39B →	+4.584	+4.584	.007	.007	1	4
BLOOD_Lymphoma	SCAF8 →	+4.584	+4.584	.007	.007	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,031 associations by consensus.

HINFP by ABHD2 expression — SKIN

Explore this box plot interactively →