ABHD18

Across TCGA patient cohorts, ABHD18 mutation is significantly associated with the RNA expression of many other genes, with 737 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABHD18-associated genes across cancer lineages are RN7SL483P, CKAP2L, and MNAT1. Each is linked with ABHD18 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABHD18-to-partner and partner-to-ABHD18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL483P grouped by ABHD18-low versus ABHD18-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD18→partner) and Y-score (partner→ABHD18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL483P →	+0.184	+5.362	<.001	.005	3	2
UCEC	CKAP2L →	+0.734	+3.595	.009	.001	3	2
UCEC	MNAT1 →	+0.589	+3.475	.005	.002	3	2
UCEC	KPNA6 →	+0.699	+3.584	.001	.003	3	2
UCEC	CFAP20 →	+0.522	+3.387	.006	.004	3	2
HNSC	RPL12P3 →	+0.110	+5.505	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 737 associations by consensus.

RN7SL483P by ABHD18 expression — SKCM

Explore this box plot interactively →