ABHD18

Across TCGA patient cohorts, ABHD18 mutation is significantly associated with the total protein of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABHD18-associated genes across cancer lineages are Caspase-7-cleavedD198, INPP4B, and PREX1. Each is linked with ABHD18 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABHD18-to-partner and partner-to-ABHD18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by ABHD18-low versus ABHD18-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD18→partner) and Y-score (partner→ABHD18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.641	+3.019	.031	.019	3	2
COAD	INPP4B →	-0.519	-2.991	.007	.036	3	1
COAD	PREX1 →	+0.281	+3.025	.009	.019	3	1
COAD	Stathmin →	+0.223	+3.008	.005	.019	3	1
COAD	ASNS →	+0.575	+3.008	.005	.019	3	1
UCEC	JNK_pT183_Y185 →	-0.175	-2.308	.038	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Caspase-7-cleavedD198 by ABHD18 expression — UCEC

Explore this box plot interactively →