ABHD18

Across TCGA cell cohorts, ABHD18 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible ABHD18-associated genes across cancer lineages are PDILT, RESP18, and KRTAP16-1. Each is linked with ABHD18 in more than 1 cancer types. Because this analysis shows association rather than direction, both ABHD18-to-partner and partner-to-ABHD18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PDILT grouped by ABHD18-low versus ABHD18-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD18→partner) and Y-score (partner→ABHD18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	PDILT →	+0.051	+4.415	<.001	.007	3	1
UPPER_AERODIGESTIVE_TRACT	RESP18 →	+0.040	+5.357	<.001	.003	3	1
UPPER_AERODIGESTIVE_TRACT	KRTAP16-1 →	+0.006	+4.736	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

PDILT by ABHD18 expression — SKIN

Explore this box plot interactively →