ABHD17C

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ABHD17C mutation is significantly associated with the RNA expression of many other genes, with 76 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABHD17C-associated genes across cancer lineages are ATP6V1E1P2, RN7SL419P, and MIR6793. Each is linked with ABHD17C in more than 1 cancer types. Because this analysis shows association rather than direction, both ABHD17C-to-partner and partner-to-ABHD17C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP6V1E1P2 grouped by ABHD17C-low versus ABHD17C-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD17C→partner) and Y-score (partner→ABHD17C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECATP6V1E1P2 →+0.224+3.077<.001.00532
COADRN7SL419P →+0.342+5.017<.001.00932
UCECMIR6793 →+0.729+3.111.009.00431
COADLINC00208 →+0.055+5.693.008.00331
UCECMIR8070 →+0.891+3.454<.001.00131
UCECOR51C1P →+0.077+4.420<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 76 associations by consensus.

ATP6V1E1P2 by ABHD17C expression — UCEC

Box plot of ATP6V1E1P2 in ABHD17C-low vs ABHD17C-high samples in UCEC.

Explore this box plot interactively →

Exploration