ABHD17C

Across TCGA cell cohorts, ABHD17C mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ABHD17C-associated genes across cancer lineages are TBC1D21, TSPY2, and PYDC2. Each is linked with ABHD17C in more than 1 cancer types. Because this analysis shows association rather than direction, both ABHD17C-to-partner and partner-to-ABHD17C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TBC1D21 grouped by ABHD17C-low versus ABHD17C-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD17C→partner) and Y-score (partner→ABHD17C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TBC1D21 →	+0.015	+5.022	<.001	.002	3	1
LARGE_INTESTINE	TSPY2 →	+0.060	+5.217	<.001	<.001	3	1
LARGE_INTESTINE	PYDC2 →	+0.108	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

TBC1D21 by ABHD17C expression — LARGE_INTESTINE

Explore this box plot interactively →