ABHD17B

Across TCGA patient cohorts, ABHD17B mutation is significantly associated with the RNA expression of many other genes, with 1,236 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ABHD17B-associated genes across cancer lineages are SETP15, MIR3121, and RNU6-400P. Each is linked with ABHD17B in more than 1 cancer types. Because this analysis shows association rather than direction, both ABHD17B-to-partner and partner-to-ABHD17B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SETP15 grouped by ABHD17B-low versus ABHD17B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD17B→partner) and Y-score (partner→ABHD17B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SETP15 →	+0.126	+2.610	.003	<.001	3	2
SKCM	MIR3121 →	+0.427	+7.816	<.001	.008	3	2
SKCM	RNU6-400P →	+0.333	+7.816	<.001	.008	3	1
UCEC	COX15 →	+0.417	+3.375	<.001	.004	3	1
UCEC	INTS4 →	+0.265	+2.818	.009	.001	3	1
UCEC	LAMTOR1 →	+0.305	+2.008	.004	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,236 associations by consensus.

SETP15 by ABHD17B expression — UCEC

Explore this box plot interactively →