ABHD17B

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ABHD17B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,867 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ABHD17B-associated GO terms across cancer lineages are Regulation of chromatin organization, Regulation of heterochromatin formation, and Protein depalmitoylation. Each is linked with ABHD17B in more than 15 cancer types. Because this analysis shows association rather than direction, both ABHD17B-to-partner and partner-to-ABHD17B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of chromatin organization grouped by ABHD17B-low versus ABHD17B-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ABHD17B→partner) and Y-score (partner→ABHD17B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCRegulation of chromatin organization →+0.106+0.518<.001.003316
LUNG_SCLCRegulation of heterochromatin formation →+0.172+0.607<.001.002315
STOMACHProtein depalmitoylation →+0.151+1.064<.001.001315
LUNG_SCLCRegulation of heterochromatin organization →+0.158+0.660<.001.001314
OESOPHAGUSPositive regulation of mRNA 3'-end processing →+0.148+0.937.006.001214
SOFT_TISSUEEstablishment of mitotic sister chromatid cohesion →+0.092+0.524<.001<.001313
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,867 associations by consensus.

Regulation of chromatin organization by ABHD17B expression — LUNG_SCLC

Box plot of Regulation of chromatin organization in ABHD17B-low vs ABHD17B-high samples in LUNG_SCLC.

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Exploration